Transcription: Role in the Initiation and Replication of DNA Synthesis in Escherichia Coli and ΦX174
Document Type
Article
Publication Date
10-28-1971
Description
1. 1. The role of transcription in the initiation of DNA synthesis and elongation of the DNA chain in Escherichia coli and the bacteriophage ΦX174 has been studied. 2. 2. Concomitant transcription does not appear to be required for semiconservative DNA replication in bacteria, or for conversion of single-stranded ΦX174 DNA to the double-stranded replicative form. 3. 3. The data substantiate the requirement in bacteria for messenger RNA(s) coding for protein(s) involved in the initiation of a round of DNA replication.
Citation Information
Silverstein, S.; and Billen, D.. 1971. Transcription: Role in the Initiation and Replication of DNA Synthesis in Escherichia Coli and ΦX174. BBA Section Nucleic Acids And Protein Synthesis. Vol.247(3). 383-399. https://doi.org/10.1016/0005-2787(71)90023-2 PMID: 4942232 ISSN: 0005-2787