Effect of Low Frequency Electromagnetic Fields on [3H]Glucose Uptake in Rat Tissues
Document Type
Article
Publication Date
4-23-2007
Description
The aims of this study were to evaluate the influence of an extremely low-frequency electromagnetic field (ELF-EMF) on [3H]glucose uptake in the peripheral tissues and organs of rats. Rats were exposed to ELF-EMF (frequency-10 Hz, induction -1.8-3.8 mT) one hour daily for 14 consecutive days. Control animals were sham exposed. On the 15th day (24 hours after last exposure) rats were injected with D-[3H]-6-glucose 500μCi/kg IP. Fifteen minutes later animals were sacrificed by decapitation and peripheral tissues were excised and examined for radioactivity (desintegrations per minute, DPM/ 100 mg wet tissue weight), which expressed [3H]glucose uptake. In most of the examined tissues and organs, such as liver, kidney, heart muscle, cartilage, connective tissue, tendon and skin, [3H]glucose uptake in ELF-EMF-exposed animals was significantly higher as compared to that in the sham control. Exposure to ELF-EMF did not influence [3H]glucose uptake in the thoracic aorta and the skeletal muscle. It is concluded that ELF-EMF impacts tissue glucose uptake by facilitating glucose transport via cell membranes, dependent and probably also independent of its role in increasing insulin action in insulin-dependent tissues.
Citation Information
Sierón, A.; Brus, H.; Konecki, J.; Cieślar, G.; Szkilnik, R.; Nowak, P.; Noras; Kwieciński, A.; Kostrzewa, R. M.; and Brus, R.. 2007. Effect of Low Frequency Electromagnetic Fields on [3H]Glucose Uptake in Rat Tissues. Polish Journal of Environmental Studies. Vol.16(2). 309-312. http://www.pjoes.com/Effect-of-Low-Frequency-Electromagnetic-Fields-on-3-H-Glucose-Uptake-in-Rat-Tissues,87991,0,2.html ISSN: 1230-1485