Cytotoxicity to Allogeneic Cells in the Chicken. III. Antibody-Dependent Cell-Mediated Cytotoxicity in Normal and Agammaglobulinemic Chickens
Document Type
Article
Publication Date
11-1-1981
Description
Spleen cells from normal and Aγ chickens mediate antibody-dependent cellular cytotoxicity ADCC on syngeneic or allogeneic RBC. They are non-T, non-B cells with Fc receptors. They are nylon wool adherent; a proportion of them are also plastic adherent and inhibitable by trypan blue. They are resistant to 2000-rad γ-irradiation in vitro. Spleen cells can be armed to mediate ADCC on unsensitized target RBC by incubation with antibody.
Citation Information
Chi, David S.; and Thorbecke, G. Jeanette. 1981. Cytotoxicity to Allogeneic Cells in the Chicken. III. Antibody-Dependent Cell-Mediated Cytotoxicity in Normal and Agammaglobulinemic Chickens. Cellular Immunology. Vol.64(2). 258-266. https://doi.org/10.1016/0008-8749(81)90478-0 PMID: 7307081 ISSN: 0008-8749