The Effect of the Glutamine Analog, at-125, on the Cell Cycle of MCE-7 and BT-20 Human Breast Carcinoma Cells Using DNA Flow Cytometry
Document Type
Article
Publication Date
1-1-1980
Description
It was found by DNA flow cytometry that AT-125 preferentially inhibited the cell cycle progression in G1-phase of BT-20 more so than MCF-7 breast carcinoma cells in vitro and that cells washed free of the drug now possessed S-phase DNA content. It was also found that γ-glutamyl transpeptidase levels were more than 2 times higher in BT-20 than in MCF-7 cells.
Citation Information
Thornthwaite, J. T.; and Allen, L. M.. 1980. The Effect of the Glutamine Analog, at-125, on the Cell Cycle of MCE-7 and BT-20 Human Breast Carcinoma Cells Using DNA Flow Cytometry. Research Communications in Chemical Pathology and Pharmacology. Vol.29(2). 393-396. https://europepmc.org/article/med/6106266 PMID: 6106266 ISSN: 0034-5164