The Effect of the Glutamine Analog, at-125, on the Cell Cycle of MCE-7 and BT-20 Human Breast Carcinoma Cells Using DNA Flow Cytometry

Document Type

Article

Publication Date

1-1-1980

Description

It was found by DNA flow cytometry that AT-125 preferentially inhibited the cell cycle progression in G1-phase of BT-20 more so than MCF-7 breast carcinoma cells in vitro and that cells washed free of the drug now possessed S-phase DNA content. It was also found that γ-glutamyl transpeptidase levels were more than 2 times higher in BT-20 than in MCF-7 cells.

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