Treatment Options for Hypertriglyceridemia Pancreatitis

Authors' Affiliations

Abbey Hinton, Clinical Medical Education, Medical Student, Lincoln Memorial University- Debusk College of Osteopathic Medicine, Knoxville, TN Lauren Phemister, Clinical Medical Education, Medical Student, East Tennessee State University, Johnson City, TN James Carter IV, Clinical Medical Education, Medical Student, Lincoln Memorial University- Debusk College of Osteopathic Medicine, Knoxville, TN

Location

D.P. Culp Center Ballroom

Start Date

4-5-2024 9:00 AM

End Date

4-5-2024 11:30 AM

Poster Number

94

Name of Project's Faculty Sponsor

Erin Hood

Faculty Sponsor's Department

Internal Medicine

Classification of First Author

Clinical Doctoral Student

Competition Type

Competitive

Type

Poster Presentation

Presentation Category

Health

Abstract or Artist's Statement

Hypertriglyceridemia pancreatitis is a complex etiology causing severe morbidity and mortality. The pathophysiologic process involves buildup of excess triglycerides and fatty acids in the vascular beds of the pancreas causing inflammation and ischemia to the surrounding tissues. This can result from primary genetic predisposition or secondary lifestyle effects such as diabetes, chronic alcohol use, or certain medications. A case of a 45-year-old female with past medical history of hypertension, hyperlipidemia, hypertriglyceridemia pancreatitis, and type 2 diabetes mellitus presented to the emergency department with concerns for persistent acute abdominal pain for the past 24 hours. She denied any fever or chills but had not been able to eat since the symptoms began. Upon workup, labs displayed severely elevated amylase, lipase, and triglycerides. CT with contrast showed diffuse fatty replacement in the enlarged liver and edematous changes surrounding the pancreas highly suspicious for pancreatitis. Patient received aggressive intravenous fluids, insulin, analgesics, bowel rest and admission to the intensive care unit floor. Over the course of 48 hours, the patient improved on insulin drip, was transferred to oral medications, and discharged within a few days. This case illustrates a rare condition that causes life threatening complications if not treated. This study will review the successful treatment options utilized for this patient as well as other acute and long-term treatment options to adequately control this unique condition.

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Apr 5th, 9:00 AM Apr 5th, 11:30 AM

Treatment Options for Hypertriglyceridemia Pancreatitis

D.P. Culp Center Ballroom

Hypertriglyceridemia pancreatitis is a complex etiology causing severe morbidity and mortality. The pathophysiologic process involves buildup of excess triglycerides and fatty acids in the vascular beds of the pancreas causing inflammation and ischemia to the surrounding tissues. This can result from primary genetic predisposition or secondary lifestyle effects such as diabetes, chronic alcohol use, or certain medications. A case of a 45-year-old female with past medical history of hypertension, hyperlipidemia, hypertriglyceridemia pancreatitis, and type 2 diabetes mellitus presented to the emergency department with concerns for persistent acute abdominal pain for the past 24 hours. She denied any fever or chills but had not been able to eat since the symptoms began. Upon workup, labs displayed severely elevated amylase, lipase, and triglycerides. CT with contrast showed diffuse fatty replacement in the enlarged liver and edematous changes surrounding the pancreas highly suspicious for pancreatitis. Patient received aggressive intravenous fluids, insulin, analgesics, bowel rest and admission to the intensive care unit floor. Over the course of 48 hours, the patient improved on insulin drip, was transferred to oral medications, and discharged within a few days. This case illustrates a rare condition that causes life threatening complications if not treated. This study will review the successful treatment options utilized for this patient as well as other acute and long-term treatment options to adequately control this unique condition.