A Comparison of a New Oral Streptogramin XRP 2868 With Quinupristin- Dalfopristin Against Antibiotic-Resistant Strains of Haemophilus Influenzae, Staphylococcus Aureus, and Streptococcus Pneumoniae

Document Type

Article

Publication Date

12-1-2005

Description

A new streptogramin antibiotic XRP 2868 was compared with quinupristin-dalfopristin for inhibitory activities against antibiotic-resistant Haemophilus influenzae, Staphylococcus aureus, and Streptococcus pneumoniae. In each organism examined, XRP 2868 had an IC50 that was twofold to fivefold lower than quinupristin-dalfopristin, for inhibition of cell viability, protein synthesis, and ribosomal subunit formation.

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