Title
Soluble Dectin-1 as a Tool to Detect β-Glucans
Document Type
Article
Publication Date
7-31-2006
Description
β-Glucans are structural components of fungal cell walls which are involved in the immune recognition of fungal pathogens and possess beneficial immunomodulatory activities in isolated form. Here we have developed a soluble chimeric form of the major mammalian β-glucan receptor, Dectin-1, and demonstrate its application for the detection and characterisation of soluble and insoluble β-glucans, including fungal particles, using ELISA, flow cytometric and fluorescence-based microscopy assays.
Citation Information
Graham, Lisa; Tsoni, S. Vicky; Willment, Janet A.; Williams, David L.; Taylor, Philip R.; Gordon, Siamon; Dennehy, Kevin; and Brown, Gordon D.. 2006. Soluble Dectin-1 as a Tool to Detect β-Glucans. Journal of Immunological Methods. Vol.314(1-2). 164-169. https://doi.org/10.1016/j.jim.2006.05.013 PMID: 16844139 ISSN: 0022-1759