Preparation, Characterization, and Use of Antioxidant-Liposomes
Document Type
Article
Publication Date
12-1-2008
Description
Antioxidant liposomes provide a unique means of delivering both water and/or lipid soluble antioxidants to tissues thereby affecting disease states or signal transduction pathways modulated by oxidative stress. Considerable evidence suggests that liposome-encapsulated antioxidants can be superior to the corresponding free antioxidants in this regard. This chapter will provide practical details on the preparation, characterization, and use of antioxidant liposomes. Methods will be described for the small-scale preparation (1 ml) and large-scale (100 ml/hour) preparation of antioxidant liposomes as well as the techniques for characterizing their size distribution and their physical and chemical stability. The use of antioxidant liposomes in an in vitro situation will also be detailed.
Citation Information
Yang, Hongsong; Paromov, Victor; Smith, Milton; and Stone, William L.. 2008. Preparation, Characterization, and Use of Antioxidant-Liposomes. Methods in Molecular Biology. Vol.477 277-292. https://doi.org/10.1007/978-1-60327-517-0_21 PMID: 19082954 ISSN: 1064-3745 ISBN: 9781603272186