Simple Synthesis of Fresh Alkyl Iodides Using Alcohols and Hydriodic Acid
Document Type
Article
Publication Date
4-14-2008
Description
A simple synthesis of fresh alkyl iodides using alcohols and hydriodic acid (HI) is reported. The alkyl iodides were obtained in quick and easy work-up with good to excellent yields (66-94%) and very high purities (97-99%). Freshly prepared iodomethane and 1-iodobutane were applied to synthesize biologically relevant 3,7-dimethyladenine and 9-butyladenine, which were characterized thoroughly using 1D and 2D NMR, individually.
Citation Information
Klein, Suzane; Zhang, Cungen; and Jiang, Yu Lin. 2008. Simple Synthesis of Fresh Alkyl Iodides Using Alcohols and Hydriodic Acid. Tetrahedron Letters. Vol.49(16). 2638-2641. https://doi.org/10.1016/j.tetlet.2008.02.106 ISSN: 0040-4039