Bioluminescent Model for the Quantification of Photothermal Ablative Breast Cancer Therapy Mediated by Near-Infrared Nanoparticles

Document Type

Conference Proceeding

Publication Date

11-9-2010

Description

Multifunctional theranostic nanoparticles hold promise for enabling non-invasive image guided cancer therapy such as photothermal therapy. Human breast tumor models in which response to image guided therapy can quickly and non-invasively be determined are needed to facilitate translation and application of these technologies. We hypothesize that a system utilizing a murine light-reporter mammary tumor cell line and near-infrared nanoparticles (NIR-NP) can be used to quantify response to therapy and determine fate of nanoparticles following photothermal ablation.

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