Bioluminescent Model for the Quantification of Photothermal Ablative Breast Cancer Therapy Mediated by Near-Infrared Nanoparticles
Document Type
Conference Proceeding
Publication Date
11-9-2010
Description
Multifunctional theranostic nanoparticles hold promise for enabling non-invasive image guided cancer therapy such as photothermal therapy. Human breast tumor models in which response to image guided therapy can quickly and non-invasively be determined are needed to facilitate translation and application of these technologies. We hypothesize that a system utilizing a murine light-reporter mammary tumor cell line and near-infrared nanoparticles (NIR-NP) can be used to quantify response to therapy and determine fate of nanoparticles following photothermal ablation.
Citation Information
Gutwein, L.; Singh, A. K.; Hahn, M.; Rule, M.; Brown, S.; Knapik, J.; Moudgil, B.; and Grobmyer, S.. 2010. Bioluminescent Model for the Quantification of Photothermal Ablative Breast Cancer Therapy Mediated by Near-Infrared Nanoparticles. Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy - Technical Proceedings of the 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010. Vol.3 386-389. https://briefs.techconnect.org/wp-content/volumes/Nanotech2010v3/pdf/891.pdf ISBN: 9781439834152