Glatiramer Acetate-Induced Lobular Panniculitis and Skin Necrosis
Document Type
Article
Publication Date
1-1-2015
Description
Glatiramer acetate (GA) is a drug that commonly is used for the treatment of relapsing-remitting multiple sclerosis (RRMS). Although it typically is known as a safe and effective therapy, a number of adverse effects associated with GA have been reported in the literature. Local injection-site reactions (LISRs) and mild systemic symptoms are among the most commonly described adverse effects. A review of the literature revealed limited reports of panniculitis as an adverse effect of GA injection and even fewer describing associated skin necrosis. We report a case of GA-induced panniculitis and skin necrosis and discuss the occurrence of panniculitis, necrosis, and lipoatrophy following GA injections.
Citation Information
Watkins, Casey E.; Litchfield, John; Youngberg, George; Leicht, Stuart S.; and Krishnaswamy, Guha. 2015. Glatiramer Acetate-Induced Lobular Panniculitis and Skin Necrosis. Cutis. Vol.95(3). E26-E30. https://www.mdedge.com/dermatology/article/97844/dermatopathology/glatiramer-acetate-induced-lobular-panniculitis-and-skin PMID: 25844792 ISSN: 0011-4162