Targeted Thromboelastographic (TEG) Blood Component and Pharmacologic Hemostatic Therapy in Traumatic and Acquired Coagulopathy
Document Type
Article
Publication Date
6-1-2016
Description
Trauma-induced coagulopathy (TIC) is a recently described condition which traditionally has been diagnosed by the common coagulation tests (CCTs) such as prothrombin time/international normalized ratio (PT/INR), activated partial thromboplastin time (aPTT), platelet count, and fibrinogen levels. The varying sensitivity and specificity of these CCTs have led trauma coagulation researchers and clinicians to use Viscoelastic Tests (VET) such as Thromboelastography (TEG) to provide Targeted Thromboelastographic Hemostatic and Adjunctive Therapy (TTHAT) in a goal directed fashion to those trauma patients in need of hemostatic resuscitation. This review describes the utility of VETs, in particular, TEG, to provide TTHAT in trauma and acquired non-trauma-induced coagulopathy.
Citation Information
Walsh, Mark; Fritz, Stephanie; Hake, Daniel; Son, Michael; Greve, Sarah; Jbara, Manar; Chitta, Swetha; Fritz, Braxton; Miller, Adam; Bader, Mary K.; McCollester, Jonathon; Binz, Sophia; Liew-Spilger, Alyson; Thomas, Scott; Crepinsek, Anton; Shariff, Faisal; Ploplis, Victoria; and Castellino, Francis. 2016. Targeted Thromboelastographic (TEG) Blood Component and Pharmacologic Hemostatic Therapy in Traumatic and Acquired Coagulopathy. Current Drug Targets. Vol.17(8). 954-970. https://doi.org/10.2174/1389450117666160310153211 PMID: 26960340 ISSN: 1389-4501