Intrauterine Cerebral Infarcts and Bilateral Frontal Cortical Leukomalacia Following Chronic Maternal Inhalation of Carburetor Cleaning Fluid During Pregnancy

Document Type

Article

Publication Date

12-1-2003

Description

Little is know about the effect of inhalation of methanol and other solvents on the pregnancy and the growth of the fetus. We report a preterm male infant who developed cerebral infarcts in utero, leading to large areas of bilateral frontal cortical leukomalacia following chronic maternal inhalation of carburetor-cleaning fluid during pregnancy. The infant presented with acute fetal distress with significant metabolic acidosis at birth. Initial hypotonia was followed by generalized hypertonicity. This infant did not exhibit typical facial features of fetal alcoholic syndrome.

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