Serologically Documented Loracarbef (Lorabid)-Induced Immune Thrombocytopenia

Document Type

Article

Publication Date

5-1-2003

Description

We report here the first case of severe Immune thrombocytopenia induced by a secondgeneration cephalosporin antibiotic, Loracarbef. A 56-year old white female developed acute severe thrombocytopenia associated with acute respiratory symptoms following administration of Loracarbef. She responded to Loracarbef withdrawal and systemic corticosteroid administration. Loracarbef-dependent platelet-reactive antibodies were demonstrable in her serum by flow cytometry.

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