Myxedema Coma: The Prognosis is Improving

Document Type

Article

Publication Date

1-1-1993

Description

Insights into the physiology of thyroid hormone deficiency and the elucidation of thyroid hormone action at the cellular and molecular level have improved our understanding of the pathophysiology of myxedema coma. In the past, the mortality rate of this condition was 70–80%. Over the last 10–15 years, however, patients are recognized earlier, receiving intensive supportive care, and are treated with thyroxine early in the course of their illness. These factors have greatly improved the prognosis of myxedema coma and reduced the mortality rate to about 20%.

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