Melancholia With Onset During Treatment With SSRIs
Document Type
Article
Publication Date
12-1-1998
Description
A defined group of medical records was surveyed for patients who showed onset of major depression with melancholic features while taking an antidepressant medication. Nine cases resulted. In all the antidepressants being taken while melancholia began were SSRIs and the melancholic depression remitted rapidly with the first treatment given, bupropion in five males, nortriptyline with triiodothyronine in two females, and ECT in one male and one female. This suggests that patients who take SSRIs and are melancholic respond well to bupropion, nortriptyline, or ECT. These observations complement reports of low responsivity of melancholic depression to SSRIs and distinctions between melancholic and nonmelancholic depressions.
Citation Information
Swartz, Conrad M.; and Guadagno, Gina. 1998. Melancholia With Onset During Treatment With SSRIs. Annals of Clinical Psychiatry. Vol.10(4). 177-179. https://doi.org/10.1023/A:1022398213729 PMID: 9988059 ISSN: 1040-1237