Maternal Protection Against Escherichia Coli Kl Infection in a Neonatal Rat Model
Document Type
Article
Publication Date
7-1-1984
Description
Maternal protection against Escherichia coli Kl meningitis in a neonatal rat model was studied. Mothers immunized with formalin-killed and live E. coli Kl had detectable levels of antibody in both serum and colostrum. After orogastric challenge with E. coli Kl, 34% of pups born to and nursed by immunized mothers were found to be bacteremic compared to 60% of those born to and nursed by nonimmunized mothers. Thus, nothers immunized with E. coli Kl organisms prior to delivery can provide protection against subsequent development of Kl meningitis in the neonate.
Citation Information
Berk, Steven L.; Neumann, Phyllis; and Chi, David. 1984. Maternal Protection Against Escherichia Coli Kl Infection in a Neonatal Rat Model. Current Microbiology. Vol.10(4). 211-213. https://doi.org/10.1007/BF01627257 ISSN: 0343-8651