Absence of Sprouting by Retinogeniculate Axons After Chronic Focal Lesions in the Adult Cat Retina

Creator(s)

R. H. Baisden, East Tennessee State UniversityFollow
E. H. Polley, University of Illinois
D. C. Goodman, SUNY Upstate Medical University
E. D. Wolf, University of Illinois at Chicago

Document Type

Article

Publication Date

1-1-1980

Description

Focal lesions were placed in the retina of adult cats in order to denervate partially the laminae of the lateral geniculate nucleus (LGN). Retinogeniculate projections were assessed after survival times of from 5 days to 2 years by means of either reduced silver staining for degeneration or autoradiographic labelling. Filling of the lesion-denervated zones by 'sprouts' from the intact retinofugal fibers was not observed, even in the brains of animals with long-term lesions. It was concluded that the retinogeniculate projection in adult cat does not displat any significant ability to sprout into denervated regions.

Citation Information

Baisden, R. H.; Polley, E. H.; Goodman, D. C.; and Wolf, E. D.. 1980. Absence of Sprouting by Retinogeniculate Axons After Chronic Focal Lesions in the Adult Cat Retina. Neuroscience Letters. Vol.17(1-2). 33-38. https://doi.org/10.1016/0304-3940(80)90057-9 PMID: 7052465 ISSN: 0304-3940