Title
Postnatal Development of Phenylethanolamine-N-Methyltransferase Activity of Rat Retina
Document Type
Article
Publication Date
12-16-1987
Description
The postnatal development of rat retinal phenylethanolamine-N-methyltransferase (PNMT) activity was measured by radiometric assay. Activity was detected on day 1 of life. Retinal PNMT activity of day 1 neonates approximated 10% that of the adult. There is an increase in enzyme activity before eye opening. By day 30, enzyme activity has peaked. The enzyme during this early period possesses the same substrate specificity and inhibitor sensitivity as that of the adult enzyme. PNMT activity is detected before tyrosine hydroxylase activity.
Citation Information
Cohen, Joseph. 1987. Postnatal Development of Phenylethanolamine-N-Methyltransferase Activity of Rat Retina. Neuroscience Letters. Vol.83(1-2). 138-142. https://doi.org/10.1016/0304-3940(87)90230-8 PMID: 2894621 ISSN: 0304-3940