Cardiotoxic Manifestations of Mesoridazine Overdose

Creator(s)

Pamela A. Marrs-Simon, University of Illinois at Chicago
Michelle Zell-Kanter, University of Illinois at Chicago
Donald L. Kendzierski, University of Illinois at Chicago
Jerrold B. Leikin, Quillen-Dishner College of Medicine

Document Type

Article

Publication Date

1-1-1988

Description

We present a case of malignant arrhythmias associated with hypocalcemia and subsequent cardiac arrest in a 20-year-old woman due to ingestion of 3.1 g mesoridazine in a suicide attempt. There were unexplained alterations in serum electrolytes preceding the cardiac arrest. The patient subsequently recovered and was transferred to a psychiatric hospital. Despite the paucity of data on the potential cardiotoxicity associated with mesoridazine overdose, this case demonstrates that malignant arrhythmias and cardiac arrest occur; consequently, these patients probably require constant ECG monitoring.

Citation Information

Marrs-Simon, Pamela A.; Zell-Kanter, Michelle; Kendzierski, Donald L.; and Leikin, Jerrold B.. 1988. Cardiotoxic Manifestations of Mesoridazine Overdose. Annals of Emergency Medicine. Vol.17(10). 1074-1078. https://doi.org/10.1016/S0196-0644(88)80448-7 PMID: 3177997 ISSN: 0196-0644