Intravenous Self-Administration of Morphine by Naive Mice
Document Type
Article
Publication Date
1-1-1983
Description
A simple method for IV self-administration of drugs by mice is described. When morphine (0.5 mg/kg) was made contingent on a nosepoke response, naive mice increased their rate of nosepoking when compared either with animals receiving contingent saline vehicle injectionsor yoked control animals receiving noncontingent morphine.
Citation Information
Criswell, Hugh E.; and Ridings, Annette. 1983. Intravenous Self-Administration of Morphine by Naive Mice. Pharmacology, Biochemistry and Behavior. Vol.18(3). 467-470. https://doi.org/10.1016/0091-3057(83)90471-9 PMID: 6836001 ISSN: 0091-3057