Bright Artificial Light Produces Subsensitivity to Clonidine
Document Type
Article
Publication Date
1-1-1988
Description
The authors used a thermoregulation paradigm to test the hypothesis that chronic treatment with bright artificial light produces subsensitivity to the hypothermic effects of clonidine, an α2-agonist. One week of treatment produced blunting of the hypothermic response to clonidine (p < 0.00001). These findings are consistent with previous reports that somatic treatments for depression produce subsensitivity of the α2-receptor.
Citation Information
Dilsaver, Steven C.; and Majchrzak, Mark J.. 1988. Bright Artificial Light Produces Subsensitivity to Clonidine. Life Sciences. Vol.42(5). 597-601. https://doi.org/10.1016/0024-3205(88)90102-6 PMID: 2828797 ISSN: 0024-3205