Effects of Acute Stress on Lymphocyte B2-Adrenoceptors in White Males
Document Type
Article
Publication Date
1-1-1993
Description
The effects of acute cold pressor stress on peripheral blood cells and lymphocyte β2-adrenoceptor density and affinity were examined in 18 young, healthy normal white male volunteers. Blood samples were drawn two times before and three times after the stressor. The percents of lymphocytes and neutrophils, plasma cortisol and the β2-adrenoceptor density were significantly different among blood samples. There were no differences between samples in total white blood cell count, and percent of monocyte, basophil and eosinophil or β2-adrenoceptor affinity. The results suggest that cold pressor stress causes lymphocytosis and increases the lymphocytic β2-adrenoceptors concentration. Methodological issues, acute vs chronic condition effects, immune cell subset variations and the psychosomatic activity-affect model were discussed. Such adrenoceptor changes may provide one mechanism by which stress can affect the onset of cardiac/hypertensive disorders.
Citation Information
Chi, David S.; Neumann, Joseph K.; Mota-Marquez, Marbelyn; and Dubberley, F. Aaron. 1993. Effects of Acute Stress on Lymphocyte B2-Adrenoceptors in White Males. Journal of Psychosomatic Research. Vol.37(7). 763-770. https://doi.org/10.1016/0022-3999(93)90105-O PMID: 8229907 ISSN: 0022-3999