Biological Effects of a Purified Lipopolysaccharide From Bacteroides Gingivalis

Creator(s)

B. C. Nair, University at Buffalo, The State University of New York
W. R. Mayberry, University at Buffalo, The State University of New York
R. Dziak, University at Buffalo, The State University of New York
P. B. Chen, University at Buffalo, The State University of New York
M. J. Levine, University at Buffalo, The State University of New York
E. Hausmann, University at Buffalo, The State University of New York

Document Type

Article

Publication Date

1-1-1983

Description

Lipopolysaccharide (LPS) has been purified from Bacteroides gingivalis. The purity of this LPS is evidenced on ultracentrifugation, immunoelectrophoresis, and chemical analyses. On comparison with LPS from aerobic enteric organisms, LPS from Bacteroides gingivalis exhibits minimal potency when tested for pyrogenicity in rabbits and mitogenicity in mouse spleen cells. On the other hand, purified LPS from Bacteroides gingivalis exhibits high potency in its ability to stimulate 45Ca release from prelabeled fetal rat bones and to inhibit Ca influx into osteoclast‐like cells.

Citation Information

Nair, B. C.; Mayberry, W. R.; Dziak, R.; Chen, P. B.; Levine, M. J.; and Hausmann, E.. 1983. Biological Effects of a Purified Lipopolysaccharide From Bacteroides Gingivalis. Journal of Periodontal Research. Vol.18(1). 40-49. https://doi.org/10.1111/j.1600-0765.1983.tb00333.x PMID: 6222173 ISSN: 0022-3484