X-Linked Hypogonadism, Gynecomastia, Mental Retardation, Short Stature, and Obesity-a New Syndrome

Creator(s)

Silvia B. Vasquez, Quillen-Dishner College of Medicine
Daniel L. Hurst, Quillen-Dishner College of Medicine
Juan F. Sotos, Quillen-Dishner College of Medicine

Document Type

Article

Publication Date

1-1-1979

Description

Five male members in four generations of the same family had hypogonadism, gynecomastia, mentalretardation, obesity, and short stature. The X-linked mode of inheritance, the distinctive facies, the normal size of the hands and feet, and the true gynecomastia are the main characteristics. Endocrine evaluation and histologic studies of the testes suggest partial hypogonadotropic hypogonadism. This disorder represents a new syndrome distinct from others previously described.

Citation Information

Vasquez, Silvia B.; Hurst, Daniel L.; and Sotos, Juan F.. 1979. X-Linked Hypogonadism, Gynecomastia, Mental Retardation, Short Stature, and Obesity-a New Syndrome. The Journal of Pediatrics. Vol.94(1). 56-60. https://doi.org/10.1016/S0022-3476(79)80350-9 PMID: 758423 ISSN: 0022-3476