Dithiotosylates as Reagents in Organic Synthesis¹

Creator(s)

R. B. Woodward, Harvard University
Irwin J. Pachter, Harvard University
R. B. Woodward, East Tennessee State University

Document Type

Article

Publication Date

4-1-1971

Description

Reliable procedures for the preparation of trimethylene and ethylene dithiotosylates are reported. Techniques for the formation of dithianes and dithiolanes by reaction of these reagents with activated methylene groups are described; these include prior activation of methylene groups adjacent to carbonyl by conversion to either hydroxymethylene or enamine derivatives. Applications of dithiotosylate reactions to various aspects of organic synthesis are discussed.

Citation Information

Woodward, R. B.; Pachter, Irwin J.; and Woodward, R. B.. 1971. Dithiotosylates as Reagents in Organic Synthesis¹. Journal of Organic Chemistry. Vol.36(8). 1137-1139. https://doi.org/10.1021/jo00807a026 ISSN: 0022-3263