Vitamin a Alters the Internal Viscosity of Fragments of Limb-Bud Mesenchyme
Document Type
Article
Publication Date
1-1-1980
Description
Two techniques were used to examine the effect of vitamin A compounds (vitamin A acid = retinoic acid and vitamin A acetate) upon the relative strengths of adhesion among mouse limb-bud mesenchymal cells. Treatment with retinoic acid in vivo and with vitamin A acetate in vitro reduced the rate at which the fragments of mesenchyme rounded-up when cultured on a non-adhesive substratum, but these compounds did not alter the behavior of tissues tested in fragment-fusion experiments. These conflicting results indicate that the two tests measure different activities of cells and suggest that treatment with vitamin A alters the property(ies) of cells which regulate the internal viscosity of tissues.
Citation Information
Kwasigroch, T. E.; and Kochhar, D. M.. 1980. Vitamin a Alters the Internal Viscosity of Fragments of Limb-Bud Mesenchyme. Journal of Embryology and Experimental Morphology. Vol.VOL. 59 325-339. PMID: 7217875 ISSN: 0022-0752