Effects of Propafenone on TEA-Induced Action Potentials in Vascular Smooth Muscle of Canine Coronary Arteries

Creator(s)

D. R. Harder, East Tennessee State University
L. Belardinelli, East Tennessee State University

Document Type

Article

Publication Date

9-1-1980

Description

The Ca++-dependent, TEA-induced action potential is blocked by propafenone in a dose-dependent manner. Such results suggests that in coronary arterial smooth muscle one mechanism of action of propafenone is to inhibit Ca++ inward current.

Citation Information

Harder, D. R.; and Belardinelli, L.. 1980. Effects of Propafenone on TEA-Induced Action Potentials in Vascular Smooth Muscle of Canine Coronary Arteries. Experientia. Vol.36(9). 1082-1083. https://doi.org/10.1007/BF01965982 PMID: 7418845 ISSN: 0014-4754