Cerebellar Nuclear Lesions in Rats: Subsequent Avoidance Behavior and Ascending Anatomical Connections
Document Type
Article
Publication Date
4-20-1979
Description
Bilateral lesions of the rat cerebellar dentate and lateral interposed nuclei produced transient deficits in movement and posture, and facilitated acquisition of two-way active avoidance. Bilateral lesions of the fastigial and medial interposed nuclei of the rat cerebellum also produced transient deficits in movement and posture, but impaired acquisition of the avoidance task. Analysis of degeneration patterns after unilateral lesions to either the lateral or medial nuclear region indicated that the lateral area has a denser rostral projection than the medial area, while the medial nuclear region has a heavier caudal projection. It is suggested that these differences in anatomic connections may be related to the observed differences in lesion effect on two-way active avoidance.
Citation Information
Schneiderman Fish, Barbara; Baisden, Ronald H.; and Woodruff, Michael L.. 1979. Cerebellar Nuclear Lesions in Rats: Subsequent Avoidance Behavior and Ascending Anatomical Connections. Brain Research. Vol.166(1). 27-38. https://doi.org/10.1016/0006-8993(79)90646-2 PMID: 421154 ISSN: 0006-8993