Hemodynamic and Two-Phase Material Properties of the Arterial Wall in Rats With Heart Failure
Document Type
Conference Proceeding
Publication Date
12-1-1994
Description
Hemodynamic, passive material properties and water permeability of the carotid artery were measured in rats with heart failure produced by ligation of the coronary artery. These measurements were implemented into finite element models based on large deformation, two-phase theory. Heart failure resulted in a decrease in the radial total stress gradient across the arterial wall and an increase in the circumferential stress gradient. Treatment with captopril bur not hydralazine decrease the steady state wall stress gradients.
Citation Information
Gaballa, Mohamed A.; Raya, Thomas E.; Simon, Bruce R.; and Goldman, Steven. 1994. Hemodynamic and Two-Phase Material Properties of the Arterial Wall in Rats With Heart Failure. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol.28 3-4. https://www.ahajournals.org/doi/pdf/10.1161/01.RES.71.1.145