Inhibition of a Chicken B-Cell Lymphoma by Suppressor T-Cells From Agammaglobulinemic Chickens
Document Type
Article
Publication Date
1-1-1990
Description
The growth of B-cell lymphoma, LSCC-RP9, in culture was inhibited by spleen cells from bursa-immunized agammaglobulinemic (A-gamma) chickens. This inhibition was mediated by suppressor T-cells. The growth of transplantable LSCT-RP6 B-cell lymphoma was suppressed in A-gamma chickens, while that of the control SPCT-RP11 T-cell tumor was not affected. Furthermore, the incidence and growth of the LSCT-RP6 tumor in normal recipients were decreased when it was co-transplanted with spleen cells from bursa immunized A-gamma chickens. The results suggest that suppressor T-cells inhibit the growth of B-cell lymphoma.
Citation Information
Chi, D. S.; and Sharma, J. M.. 1990. Inhibition of a Chicken B-Cell Lymphoma by Suppressor T-Cells From Agammaglobulinemic Chickens. Anticancer Research. Vol.10(5 A). 1347-1352. https://pubmed.ncbi.nlm.nih.gov/2146919/ PMID: 2146919 ISSN: 0250-7005