Document Type
Article
Publication Date
5-1-2017
Description
Phosphatidylinositol 3-kinase δ (PIK3δ) is a tyrosine kinase essential for B cell survival, making it an important target in the treatment of chronic lymphocytic leukemia. Idelalisib is an inhibitor of PIK3δ demonstrating initial success in disease response, but is now shown to have a decreased overall survival and life-threatening serious adverse events. The following is an unfortunate case of a grade III adverse skin reaction secondary to idelalisib with the likely complication of methicillin-resistant Staphylococcus aureus bacteremia.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Citation Information
Gabriel, Joseph Gabriel; Kapila, Aaysha; and Gonzalez-Estrada, Alexei. 2017. A Severe Case of Cutaneous Adverse Drug Reaction Secondary to a Novice Drug: Idelalisib. Journal of Investigative Medicine High Impact Case Reports. Vol.5(2). https://doi.org/10.1177/2324709617711463
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