Deficiency of Ataxia Telangiectasia-Mutated Kinase (ATM) in Female Mice Preserves Heart Function in Response to Western-type Diet (WD) by Affecting Cardiac Remodeling
Faculty Mentor
Dr. Krishna Singh
Mentor Home Department
Biomedical Sciences
Short Abstract
Deficiency of ATM protein and consumption of a Western-type Diet (WD) independently associate with heart disease. Our lab has shown that ATM-deficient female mice have attenuated fat weight gain and preserved heart function in the presence of WD. Here we investigated the effect of ATM deficiency on cardiac remodeling parameters in female mice fed with WD. It is hypothesized that ATM deficiency alters myocardial remodeling in female mice, thereby preserving heart function.
Category
Science and Technology
Start Date
24-4-2023 9:30 AM
End Date
24-4-2023 9:45 AM
Location
D.P. Culp Center Room 219
Deficiency of Ataxia Telangiectasia-Mutated Kinase (ATM) in Female Mice Preserves Heart Function in Response to Western-type Diet (WD) by Affecting Cardiac Remodeling
D.P. Culp Center Room 219
Deficiency of ATM protein and consumption of a Western-type Diet (WD) independently associate with heart disease. Our lab has shown that ATM-deficient female mice have attenuated fat weight gain and preserved heart function in the presence of WD. Here we investigated the effect of ATM deficiency on cardiac remodeling parameters in female mice fed with WD. It is hypothesized that ATM deficiency alters myocardial remodeling in female mice, thereby preserving heart function.