Antagonistic Polymicrobial Inhibitory Mechanism of Enterobacter Cloacae Against Candida Albicans

Faculty Mentor

Dr. Sean Fox

Mentor Home Department

Health Sciences

Short Abstract

Microbial resistance is a significant global concern due to the current mass-production and excessive use of antibiotics. It is possible to target these resistant microorganisms by exploring polymicrobial interactions and antagonistic relationships to devise new methods of treatment. This technique has not been extensively researched—especially the antagonistic relationship between Enterobacter cloacae and Candida albicans. We have found that the E. cloacae mutant—with a SirA gene mutation—is important in this interaction with C. albicans and potential inhibition target.

Category

Science and Technology

Start Date

24-4-2023 1:15 PM

End Date

24-4-2023 1:30 PM

Location

D.P. Culp Center Room 271J

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Apr 24th, 1:15 PM Apr 24th, 1:30 PM

Antagonistic Polymicrobial Inhibitory Mechanism of Enterobacter Cloacae Against Candida Albicans

D.P. Culp Center Room 271J

Microbial resistance is a significant global concern due to the current mass-production and excessive use of antibiotics. It is possible to target these resistant microorganisms by exploring polymicrobial interactions and antagonistic relationships to devise new methods of treatment. This technique has not been extensively researched—especially the antagonistic relationship between Enterobacter cloacae and Candida albicans. We have found that the E. cloacae mutant—with a SirA gene mutation—is important in this interaction with C. albicans and potential inhibition target.