A Tri-Culture Model for Examining Polymicrobial Interactions

Faculty Mentor

Dr. Sean Fox

Mentor Home Department

Health Sciences

Short Abstract

The human oral cavity and gastrointestinal tract are full of constantly interacting microorganisms, and their balanced relationships play roles in health outcomes. Alcaligenes faecalis has an inhibitory effect on Candida albicans. Candida albicans and Streptococcus mutans share a mutualistic relationship contributing to pathogenic dental decay. This study examines effects on growth in the presence of all three organisms in a tri-culture. The experimental results could help better understand how to inhibit pathogenic microbial growth and promote oral health.

Category

Science and Technology

Start Date

24-4-2023 9:15 AM

End Date

24-4-2023 9:30 AM

Location

D.P. Culp Center Room 271J

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Apr 24th, 9:15 AM Apr 24th, 9:30 AM

A Tri-Culture Model for Examining Polymicrobial Interactions

D.P. Culp Center Room 271J

The human oral cavity and gastrointestinal tract are full of constantly interacting microorganisms, and their balanced relationships play roles in health outcomes. Alcaligenes faecalis has an inhibitory effect on Candida albicans. Candida albicans and Streptococcus mutans share a mutualistic relationship contributing to pathogenic dental decay. This study examines effects on growth in the presence of all three organisms in a tri-culture. The experimental results could help better understand how to inhibit pathogenic microbial growth and promote oral health.