Digital Commons @ East Tennessee State University - Dr. Jay W. Boland Undergraduate Research Symposium: Potential Klebsiella Bacteriocin with Efficacy Toward the Enterobacteriaceae Family

 

Potential Klebsiella Bacteriocin with Efficacy Toward the Enterobacteriaceae Family

Faculty Mentor

Dr. Sean Fox

Mentor Home Department

Health Sciences

Short Abstract

Drug resistance is a prevalent issue in patient treatment. The CDC estimates 23,000 people die yearly in the United States from antibiotic-resistant infections. Microbes produce a range of antimicrobials: antibiotics, metabolites, and lytic agents. Bacteriocins differ from antibiotics as they have a narrow killing spectrum and toxicity to bacteria. We characterized a Klebsiella bacteriocin by isolating a plasmid from Klebsiella that encodes a novel bacteriocin with efficacy towards Enterobacteriaceae family members and offers alternative treatment for drug resistant.

Category

Science and Technology

Start Date

24-4-2023 9:00 AM

End Date

24-4-2023 9:15 AM

Location

D.P. Culp Center Room 271J

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Apr 24th, 9:00 AM Apr 24th, 9:15 AM

Potential Klebsiella Bacteriocin with Efficacy Toward the Enterobacteriaceae Family

D.P. Culp Center Room 271J

Drug resistance is a prevalent issue in patient treatment. The CDC estimates 23,000 people die yearly in the United States from antibiotic-resistant infections. Microbes produce a range of antimicrobials: antibiotics, metabolites, and lytic agents. Bacteriocins differ from antibiotics as they have a narrow killing spectrum and toxicity to bacteria. We characterized a Klebsiella bacteriocin by isolating a plasmid from Klebsiella that encodes a novel bacteriocin with efficacy towards Enterobacteriaceae family members and offers alternative treatment for drug resistant.