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Theses/Dissertations from 2018

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The Combined Neuropharmacology and Toxicology of Major 'Bath Salts' Constituents MDPV, Mephedrone, and Methylone, Serena Allen

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The Effect of Alcohol Consumption on Adipokine Secretion, Ashley DeGroat

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Quantitative Studies of Amyloidogenic Protein Residue Interaction Networks and Abnormal Ammonia Metabolism in Neurotoxicity and Disease, Jeddidiah Griffin

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Metabolic Plasticity in the Cellular Stress Response, Ying Li

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HIV Integrase Inhibitor Pharmacogenetics and Clinical Outcomes: An Exploratory Association Study, Derek E. Murrell

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Effects of Gender, Age, and Nutrition on Circadian Locomotor Activity Rhythms in the Flesh Fly Sarcophaga crassipalpis, Fritz Prohaska

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Virulence Regulation in Pseudomonas aeruginosa via the Alginate Regulators, AlgU and AlgR, the posttranscriptional regulator, RsmA, and the Two-component System, AlgZ/R, Sean Stacey

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Role of Ataxia-Telangiectasia Mutated Kinase in Cardiac Autophagy and Glucose Metabolism Under Ischemic Conditions, Patsy Thrasher

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Investigating the Interaction of Monoamines and Diel Rhythmicity on Anti-Predator Behavior in an Orb-Weaving Spider, Larinioides cornutus (Araneae: Araneae), Rebecca Wilson

Theses/Dissertations from 2017

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Role of Cannabinoid Receptor Type 2 (CB2) in Late Stage Atherosclerosis, Makenzie Fulmer

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A-type Lamins in Cell Cycle Regulation, Jaime L. Parman-Ryans

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Exogenous Ubiquitin: Role in Myocardial Inflammation and Remodeling Post- Ischemia/Reperfusion Injury, Stephanie Scofield

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Role of TLRs, Hippo-YAP1 Signaling, and microRNAs in Cardiac Repair and Regeneration of Damaged myocardium During Ischemic Injury, Xiaohui Wang

Theses/Dissertations from 2016

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An Investigation into Formulation and Therapeutic Effectiveness of Nanoparticle Drug Delivery for Select Pharmaceutical Agents, Dustin Cooper

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Strategies of Balancing: Regulation of Posture as a Complex Phenomenon, Allison Leich Hilbun

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Investigation of Novel Functions for DNA Damage Response and Repair Proteins in Escherichia coli and Humans, Benjamin A. Hilton

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Exploring the Relationship Between Behaviour and Neurochemistry in the Polyphenic Spider, Anelosimus studiosus (Araneae: Theridiidae), Jennifer B. Price

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In Vitro and In Vivo Characterization of Chlamydia and HSV Co-infection, Jessica A. Slade

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A novel role of human DNA damage checkpoint protein ATR in suppressing Ca2+ overload-induced PARP1-mediated necrosis, Hui Wang-Heaton

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Pharmacokinetics, Tissue Distribution, Synergistic Activity, and Antitumor Activity of Two Isomeric Flavones, Crystal L. Whitted

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Regulation of Acute and Chronic Immune Responses by β-Arrestin2, Hui Yan

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Endothelial HSPA12B is a Novel Protein for the Preservation of Cardiovascular Function in Polymicrobial Sepsis via Exosome MiR-126, Xia Zhang

Theses/Dissertations from 2015

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Role of Ataxia Telangiectasia Mutated Kinase in the Healing Process of the Heart Following Myocardial Infarction, Laura L. Daniel

Theses/Dissertations from 2014

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Cellular-based Brain Pathology in the Anterior Cingulate Cortex of Males with Autism Spectrum Disorder, Jessica D. Crawford

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Extracellular Ubiquitin: Role in Cardiac Myocyte Apoptosis and Myocardial Remodeling, Christopher Ray Daniels

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Novel Therapeutic Approaches for Ischemic Heart and Brain Injury: Modulation of Toll-Like Receptor-Mediated Signaling Pathways and PI3K/Akt Signaling, Chen Lu

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Regulation of C-reactive Protein Gene Expression and Function, Avinash N. Thirumalai

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A Comprehensive Study of the Effects of Neurotoxins on Noradrenergic Phenotypes, Neuronal Responses and Potential Intervention by Antidepressants in Noradrenergic Cells, Yan Wang

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HIF-1α in the Heart: Provision of Ischemic Cardioprotection and Remodeling of Nucleotide Metabolism, Joe Wu

Theses/Dissertations from 2013

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An Examination of the Inhibitory Effects of Antibiotic Combinations on Ribosome Biosynthesis in Staphylococcus aureus, Justin Beach

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Genetic Imbalances in Endometriosis Detected by Oligonucleotide-Array Based Comparative Genomic Hybridization, Natalie Burke

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Arrested and Aberrant: Effects of Amoxicillin in a Murine Model of Chlamydial Infection, Regenia Beth Phillips Campbell

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Identification and Characterization of Genetic Factors Involved in Candida-Bacterial Interactions, Sean J. Fox

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Mechanisms of the Anti-Pneumococcal Function of C-Reactive Protein, Toh B. Gang

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Microsporidia Spore Adherence and Host Cell Infection In Vitro, Cory A. Leonard

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New Insights into the Roles of Human DNA Damage Checkpoint Protein ATR in the Regulation of Nucleotide Excision Repair and DNA Damage-Induced Cell Death, Zhengke Li

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Novel Ester Substrates for the Detection and Treatment of Prostate Cancer, Christopher Allen McGoldrick

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Novel Roles of Replication Protein A Phosphorylation in Cellular Response to DNA Damage, Moises A. Serrano

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Bioengineering the Expression of Active Recombinant Human Cathepsin G, Enteropeptidase, Neutrophil Elastase, and C-Reactive Protein in Yeast, Eliot T. Smith

Theses/Dissertations from 2012

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Prelamin A Influences a Program of Gene Expression In Regulation of Cell Cycle Control, Christina N. Bridges

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Detection and Purification of a Novel Natural Inhibitory Compound from an Isolated Strain of Rhodococcus Using an Agar Extraction Method, Megan Carr

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An Investigation of Bacterial Ribonucleases as an Antibiotic Target, Ashley Denise Frazier

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Stabilization of the Cardiac Nervous System During Cardiac Stress Induces Cardioprotection, David D. Gibbons

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The Effects of Nicotine Administration on Behavior and Markers of Brain Plasticity in a Rodent Model of Psychosis, Marla K. Perna

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Effects of Burn Injury on Biological Ethanol and Ethyl Glucuronide Concentrations, Trista Haupt Wright

Theses/Dissertations from 2011

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Role of Type 2 Cannabinoid Receptor (CB2) in Atherosclerosis., Courtney Denise Netherland

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Biopharmaceutic and Pharmacokinetic Studies of Sucrose Acetate Isobutyrate as an Excipient for Oral Drug Delivery., Martin Ray Tant

Theses/Dissertations from 2010

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The Effect of Sternocleidomastoid Muscle Activation Pattern and Feedback Condition on the Vestibular Evoked Myogenic Potential., Mary Jo Davenport

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Mosaic Analysis with Double Markers (MADM) as a Method to Map Cell Fates in Adult Mouse Taste Buds., Preston D. Moore

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The Multifaceted Contribution of Natural Killer Cells During Herpes Simplex Type-1 Viral Infection., Stacie N. Woolard

Theses/Dissertations from 2009

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Determining Putative Secondary Product Glucosyltransferase Expression During Citrus paradisi Growth and Development., Jala Daniel

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Dopamine D2 Receptor Priming Enhances Dopaminergic Response to Amphetamine in the Nucleus Accumbens: Role of the D1 and D2 Receptors., Kimberly Norris Huggins

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Localization of Calbindin-D28k in Extra-Embryonic Membranes of Two Oviparous Scincid Lizards., Shuo Li

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Nectin-1 is Degraded in Chlamydia trachomatis-Infected Genital Epithelial Cells and is Required for Herpes Simplex Virus Co-Infection-Induced C. trachomatis Persistence., Jingru Sun

Theses/Dissertations from 2008

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Elucidating the Role of the α7 Nicotinic Receptor in the Etiology of Schizophrenia., Michelle Johnson Chandley

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Identification of Chlamydial Iron-Responsive Proteins during Intracellular Growth., Brian D. Dill

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Antigen Trafficking within Chlamydia trachomatis-Infected Polarized Human Endometrial Epithelial Cells., David Kelley Giles

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Urinary Excretion of (1-3)-Beta-D-Glucans., Debra K. Head

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Expression, Purification, and Characterization of the Mast Cell Proteases Chymase and Cathepsin G., Brent E. Lockhart

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Characterization of Murine Cardiac Cholinergic Innervation and Its Remodeling in Type 1 Diabetes., Abigail Marie Mabe

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Structural and Biochemical Investigation of the Molecular Mechanisms of DNA Response and Repair in Humans and Escherichia coli., Steven Michael Shell

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Characterization of Heat Shock Protein A12B as a Novel Angiogenesis Regulator., Rebecca J. Steagall

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Herpes Simplex Virus Glycoprotein D/Host Cell Surface Interaction Stimulates Chlamydia trachomatis Persistence via a Novel Pathway., Jennifer Vanover

Theses/Dissertations from 2007

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Characterization of a 30S Ribsomal Subunit Intermediate Found in Escherichia coli Cells Growing with Neomycin and Paromomycin., Cerrone Renee Foster

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Localization of a Microsporidia ADAM (A Disintegrin and Metalloprotease Domain) Protein and Identification of Potential Binding Partners., Carrie E. Jolly

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T-cell Dysfunction by HCV Core Protein Involves PD-1/PD-L1 Signaling., Billy Ellis King

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1, Structural and Functional Studies of Human Replication Protein A; 2 DNA Damage Responses and DNA Repair Defects in Laminopathy-Based Premature Aging., Yiyong Liu

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Antibiotics that Inhibit 30S or 50S Ribosomal Subunit Formation: Hygromycin B, Quinupristin-Dalfopristin and XRP 2868., Susan Mabe McGaha

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Molecular Mechanisms of Interleukin-1beta-Stimulated Regulation of Angiogenesis in Cardiac Microvascular Endothelial Cells., Deidra Jill Hopkins Mountain

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Studies on a 50S Ribosomal Precursor Particle as a Substrate for erm E Methyltransferase Enzyme in Staphylococcus aureus ., Indira Pokkunuri

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Examination of Microsporidia Spore Adherence and Host Cell Infection In Vitro., Timothy Robert Southern

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Periplasmic Modification of the 1-Phosphate Group of Lipid A in Gram-Negative Bacteria., An Xuong Tran

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Mechanism of Transcriptional Regulation of C-Reactive Protein Gene Expression., Bhavya Voleti

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Novel Protective Agents against Cerebral Ischemia/Reperfusion Injury., Xingshun Xu

Theses/Dissertations from 2006

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Dectin-1 Expression is Altered by Fungal Infection, Polymicrobial Sepsis, and Glucan Administration., Tammy Regena Ozment-Skelton

Theses/Dissertations from 2005

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Role of Zmpste24 in Prelamin A Maturation., Douglas Paul Corrigan

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Induction of the Chlamydia trachomatis Persistent State by Herpes simplex Virus Type 2 Does Not Require Productive Viral Replication., Srilekha Deka

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The Signaling Pathway of Oxysterol-Induced Apoptosis in Macrophages., Natalie Elaine Freeman

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Angiogenesis and Myogenesis in a Chronic Ischemic Heart., Esha Ibrahim

Theses/Dissertations from 2004

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Papain: a Novel Urine Adulterant., David Burrows

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Peptide Antisera Generation against Three Chlamydia trachomatis Hsp60 Homologues to Examine Expression of each Hsp60 during Iron Restrictive Growth., Richard Wayne LaRue

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Role of Macrophage Apoptosis in Atherosclerosis., June Liu

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Nongenomic Effects of Estrogens on Epithelial Chloride Secretion., Sabyasachi Moulik

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Dose-Dependent Effects of Salmon Calcitonin on Bone Turnover in Ovariectomized Rats., Beatrice H. Owens

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Degradation of 23S rRNA in Azithromycin-Treated Ribonuclease Mutants of Escherichia coli., Jessica A. Silvers

Theses/Dissertations from 2003

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Creating Genetic Engineering Tools for Investigating Bacillus anthracis., Robert Clayton Anderson III

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Flavone: the Molecular and Mechanistic Study of How a Simple Flavonoid Protects DNA from Oxidative Damage., Jennifer Dawn Dean

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Protection of Pifithrin-α and Melatonin against Doxorubicin-Induced Cardiotoxicity., Xuwan Liu

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The Role of ERp57 in Hras Intracellular Trafficking and Function., Jaime Lyn Parman

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Cocaine- and Amphetamine-Regulated Transcript Peptide Attenuates Baroreflex in the Rat., Phouangmala C. Scruggs

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Characterization of Sympathetic Ganglion Sensitivity to Substance P in a Genetic and a Non-Genetic Rat Model of Hypertension., John Daniel Tompkins

Theses/Dissertations from 2002

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Dose-Response Effects of Lithium on Spatial Memory in the Black Molly Fish., Thomas Kyle Creson

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HIV Tat Protein Activates Endothelial Cells through NFκB and MAP Kinase Pathways., Jason L. Henry

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Activation of Ca2+-activated K+ Channels and Cell Migration by Hepatocyte Growth Factor/Scatter Factor in Madin-Darby Canine Kidney Cells., Min Jin

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A New Immunoassay for Quantification of a Novel Cancer Antigen in Serum and Immunostaining of Carcinoma Tissues and Cultured Cells Revealing the Antigenic Cellular Location., Emily Christine McDuffee

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30S Ribosomal Subunit Assembly is a Target for Inhibition by Aminoglycoside Antibiotics in Escherichia coli., Roopal Manoj Mehta

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The Effect of Acute Exercise on Neutrophils and Oxidative Stress., John Carl Quindry

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The Signaling Pathway of Oxysterol Induced Apoptosis in Chinese Hamster Ovary (CHO)-K1 Cells., Lin Yang

Theses/Dissertations from 2001

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Melatonin's Protection against DNA Damage by the Iron (III)-Adriamycin Complex., Sharon E. Campbell

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Molecular Studies involving the Rev Protein of Caprine Arthritis Encephalitis Virus and Visna Virus., Bridget Michele Graves