EXPLORING THE ASSOCIATION BETWEEN SMOKELESS TOBACCO USE AND COLORECTAL CANCER: A COMPREHENSIVE ANALYSIS OF PREVALENCE AND MORTALITY IN THE US POPULATION
Location
D.P. Culp Center Ballroom
Start Date
4-5-2024 9:00 AM
End Date
4-5-2024 11:30 AM
Poster Number
82
Name of Project's Faculty Sponsor
Puneet Goenka
Faculty Sponsor's Department
Division of Gastroenterology
Competition Type
Competitive
Type
Poster Presentation
Presentation Category
Health
Abstract or Artist's Statement
This study aims to evaluate the prevalence and mortality disparities among individuals using smokeless tobacco. Utilizing data from the National Longitudinal Mortality Sample provided by NHLBI, we conducted a retrospective cohort study to explore the correlation between smokeless tobacco use and colorectal cancer. To ensure the sample's representativeness, weights were applied to address selection and nonresponse probabilities. The dataset comprised information on 138,352,018 patients over five years, reflecting the demographic characteristics of the general population, including a mean age of 45 ± 26.7 and a gender distribution of 65,417,216 (47.2%) males and 72,934,802 (52.7%) females. Among this patient cohort, 149,417 individuals died from colorectal cancer. Within this subset, 6,441 individuals (4.3%) who succumbed to colorectal cancer had a reported history of smokeless tobacco use, while 142,976 individuals did not have any history of smokeless tobacco usage. The association between smokeless tobacco and colorectal cancer mortality was examined using the Pearson Chi-Square test, revealing a relative risk of 2.02 [confidence interval: 1.42-3.48] with a p-value of 0.15.
EXPLORING THE ASSOCIATION BETWEEN SMOKELESS TOBACCO USE AND COLORECTAL CANCER: A COMPREHENSIVE ANALYSIS OF PREVALENCE AND MORTALITY IN THE US POPULATION
D.P. Culp Center Ballroom
This study aims to evaluate the prevalence and mortality disparities among individuals using smokeless tobacco. Utilizing data from the National Longitudinal Mortality Sample provided by NHLBI, we conducted a retrospective cohort study to explore the correlation between smokeless tobacco use and colorectal cancer. To ensure the sample's representativeness, weights were applied to address selection and nonresponse probabilities. The dataset comprised information on 138,352,018 patients over five years, reflecting the demographic characteristics of the general population, including a mean age of 45 ± 26.7 and a gender distribution of 65,417,216 (47.2%) males and 72,934,802 (52.7%) females. Among this patient cohort, 149,417 individuals died from colorectal cancer. Within this subset, 6,441 individuals (4.3%) who succumbed to colorectal cancer had a reported history of smokeless tobacco use, while 142,976 individuals did not have any history of smokeless tobacco usage. The association between smokeless tobacco and colorectal cancer mortality was examined using the Pearson Chi-Square test, revealing a relative risk of 2.02 [confidence interval: 1.42-3.48] with a p-value of 0.15.