EXPLORING THE ASSOCIATION BETWEEN SMOKELESS TOBACCO USE AND COLORECTAL CANCER: A COMPREHENSIVE ANALYSIS OF PREVALENCE AND MORTALITY IN THE US POPULATION

Authors' Affiliations

Hezborn Magacha, MD, Department of Internal Medicine, East Tennessee State University Pooja Bhandari, Department of Neurology, University of Missisippi Medical Center

Location

D.P. Culp Center Ballroom

Start Date

4-5-2024 9:00 AM

End Date

4-5-2024 11:30 AM

Poster Number

82

Name of Project's Faculty Sponsor

Puneet Goenka

Faculty Sponsor's Department

Division of Gastroenterology

Classification of First Author

Medical Resident or Clinical Fellow

Competition Type

Competitive

Type

Poster Presentation

Presentation Category

Health

Abstract or Artist's Statement

This study aims to evaluate the prevalence and mortality disparities among individuals using smokeless tobacco. Utilizing data from the National Longitudinal Mortality Sample provided by NHLBI, we conducted a retrospective cohort study to explore the correlation between smokeless tobacco use and colorectal cancer. To ensure the sample's representativeness, weights were applied to address selection and nonresponse probabilities. The dataset comprised information on 138,352,018 patients over five years, reflecting the demographic characteristics of the general population, including a mean age of 45 ± 26.7 and a gender distribution of 65,417,216 (47.2%) males and 72,934,802 (52.7%) females. Among this patient cohort, 149,417 individuals died from colorectal cancer. Within this subset, 6,441 individuals (4.3%) who succumbed to colorectal cancer had a reported history of smokeless tobacco use, while 142,976 individuals did not have any history of smokeless tobacco usage. The association between smokeless tobacco and colorectal cancer mortality was examined using the Pearson Chi-Square test, revealing a relative risk of 2.02 [confidence interval: 1.42-3.48] with a p-value of 0.15.

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Apr 5th, 9:00 AM Apr 5th, 11:30 AM

EXPLORING THE ASSOCIATION BETWEEN SMOKELESS TOBACCO USE AND COLORECTAL CANCER: A COMPREHENSIVE ANALYSIS OF PREVALENCE AND MORTALITY IN THE US POPULATION

D.P. Culp Center Ballroom

This study aims to evaluate the prevalence and mortality disparities among individuals using smokeless tobacco. Utilizing data from the National Longitudinal Mortality Sample provided by NHLBI, we conducted a retrospective cohort study to explore the correlation between smokeless tobacco use and colorectal cancer. To ensure the sample's representativeness, weights were applied to address selection and nonresponse probabilities. The dataset comprised information on 138,352,018 patients over five years, reflecting the demographic characteristics of the general population, including a mean age of 45 ± 26.7 and a gender distribution of 65,417,216 (47.2%) males and 72,934,802 (52.7%) females. Among this patient cohort, 149,417 individuals died from colorectal cancer. Within this subset, 6,441 individuals (4.3%) who succumbed to colorectal cancer had a reported history of smokeless tobacco use, while 142,976 individuals did not have any history of smokeless tobacco usage. The association between smokeless tobacco and colorectal cancer mortality was examined using the Pearson Chi-Square test, revealing a relative risk of 2.02 [confidence interval: 1.42-3.48] with a p-value of 0.15.