Melanosis Vesicae found in Female with Urinary Retention, Case Report

Authors' Affiliations

Andrea Smith, Quillen College of Medicine, East Tennessee State University, Johnson City, TN. R. Keith Huffaker, Department of Obstetrics and Gynecology, East Tennessee State University, Johnson City, TN. Natalie Broadway-Robertson, Department of Obstetrics and Gynecology, East Tennessee State University, Johnson City, TN.

Location

Culp Center Ballroom

Start Date

4-25-2023 9:00 AM

End Date

4-25-2023 11:00 AM

Poster Number

91

Faculty Sponsor’s Department

Obstetrics & Gynecology

Name of Project's Faculty Sponsor

R. Keith Huffaker

Classification of First Author

Medical Student

Competition Type

Competitive

Type

Poster Case Study Presentation

Project's Category

Urogenital System, Urogenital Diseases

Abstract or Artist's Statement

Melanosis vesicae (or bladder melanosis) is a rare, benign condition referring to the presence of dark pigmented melanin deposits usually within the bladder mucosa. The clinical presentation can be mistaken for primary or metastatic melanoma of the bladder, and thus a histologic assessment is useful for ruling out a malignant diagnosis. All documented cases of melanosis vesicae have presented with urinary symptoms, including hematuria, symptoms of cystitis, incontinence and obstruction. This is a case report presenting a 57-year-old female with complaints of incomplete bladder emptying who met criteria for urinary retention. She underwent in-office cystoscopy and was found to have suspected melanosis vesicae. The diagnosis was later confirmed on pathology following a bladder biopsy. The next phase in care for this patient is planned sacral neuromodulation for treatment of urinary retention. Previous case reports of bladder melanosis have suggested an association with melanin deposition and inflammatory mechanisms and have not demonstrated malignant transformation during follow up. This is, to our knowledge, the first report of documented bladder melanosis in conjunction with urinary retention. Further studies are required to understand the etiology, clinical significance, and clinical correlation of melanosis vesicae with urinary dysfunction.

This document is currently not available here.

Share

COinS
 
Apr 25th, 9:00 AM Apr 25th, 11:00 AM

Melanosis Vesicae found in Female with Urinary Retention, Case Report

Culp Center Ballroom

Melanosis vesicae (or bladder melanosis) is a rare, benign condition referring to the presence of dark pigmented melanin deposits usually within the bladder mucosa. The clinical presentation can be mistaken for primary or metastatic melanoma of the bladder, and thus a histologic assessment is useful for ruling out a malignant diagnosis. All documented cases of melanosis vesicae have presented with urinary symptoms, including hematuria, symptoms of cystitis, incontinence and obstruction. This is a case report presenting a 57-year-old female with complaints of incomplete bladder emptying who met criteria for urinary retention. She underwent in-office cystoscopy and was found to have suspected melanosis vesicae. The diagnosis was later confirmed on pathology following a bladder biopsy. The next phase in care for this patient is planned sacral neuromodulation for treatment of urinary retention. Previous case reports of bladder melanosis have suggested an association with melanin deposition and inflammatory mechanisms and have not demonstrated malignant transformation during follow up. This is, to our knowledge, the first report of documented bladder melanosis in conjunction with urinary retention. Further studies are required to understand the etiology, clinical significance, and clinical correlation of melanosis vesicae with urinary dysfunction.