Development of Metastatic Merkel Cell Carcinoma Following the Excision of Same-Sided Recurrent Auricular Melanoma

Authors' Affiliations

Jake K. Cartwright, Quillen College of Medicine, East Tennessee State University, Johnson City, TN Daniel H. Snyder, Knoxville FNA Clinic, Knoxville, TN Francisco G. Moreno, Otolaryngology—Head and Neck Surgery, Facial Plastic Surgery, Knoxville, TN

Location

Culp Room 304

Start Date

4-6-2022 9:00 AM

End Date

4-6-2022 10:00 AM

Faculty Sponsor’s Department

Other - please list

Community Medicine

Name of Project's Faculty Sponsor

Francisco Moreno

Classification of First Author

Medical Student

Competition Type

Competitive

Type

Oral Case Study Presentation

Project's Category

Cancer or Carcinogenesis

Abstract or Artist's Statement

Merkel cell carcinoma (MCC) is a rare neuroendocrine malignancy of the skin that is highly aggressive and often metastasizes early. MCC is diagnosed based on histopathological findings and is most commonly treated with surgical resection, which may be accompanied by chemotherapy and/or radiation. This report describes a 55-year-old male with history of recurrent malignant melanoma of the right pinna and subsequent excision. Three years following the excision of melanoma, he presents with a lesion to the right forehead as well as a right-sided neck mass that were found to be metastatic Merkel cell carcinoma. Although there have been reports describing the development of second cancers following the treatment of MCC, the development of MCC after the treatment of other malignancies has not been well-described. Merkel cell carcinoma remains a highly aggressive and frequently metastatic malignancy that should not be overlooked, especially when developed after the diagnosis and treatment of other primary cutaneous malignancies such as melanoma.

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Apr 6th, 9:00 AM Apr 6th, 10:00 AM

Development of Metastatic Merkel Cell Carcinoma Following the Excision of Same-Sided Recurrent Auricular Melanoma

Culp Room 304

Merkel cell carcinoma (MCC) is a rare neuroendocrine malignancy of the skin that is highly aggressive and often metastasizes early. MCC is diagnosed based on histopathological findings and is most commonly treated with surgical resection, which may be accompanied by chemotherapy and/or radiation. This report describes a 55-year-old male with history of recurrent malignant melanoma of the right pinna and subsequent excision. Three years following the excision of melanoma, he presents with a lesion to the right forehead as well as a right-sided neck mass that were found to be metastatic Merkel cell carcinoma. Although there have been reports describing the development of second cancers following the treatment of MCC, the development of MCC after the treatment of other malignancies has not been well-described. Merkel cell carcinoma remains a highly aggressive and frequently metastatic malignancy that should not be overlooked, especially when developed after the diagnosis and treatment of other primary cutaneous malignancies such as melanoma.