Purification of Cyclohexene for Cyclopropanation Reactions
Location
BEECH MTN. ROOM 120
Start Date
4-12-2019 1:00 PM
End Date
4-12-2019 1:15 PM
Faculty Sponsor’s Department
Chemistry
Name of Project's Faculty Sponsor
Dr. Cassandra Eagle
Type
Oral Presentation
Project's Category
Chemicals and Chemical Properties
Abstract or Artist's Statement
Environmentally friendly reactions yielding cis-cyclopropanes are desired in the insecticide industry as these are most effective at reducing the population of insects while remaining benign to the environment. We are exploring the best parameters for the most effective cis-cyclopropanation reactions. An alkene and a diazo compound react together in the presence of a dirhodium catalyst to produce cyclopropanes. First however, the starting materials must be pure. Alfa Aesar supplies cyclohexene which is reported to be 99% pure, however, Gas column chromatography/Mass spectroscopy reveals that the sample is only 3% cyclohexene. Using an adopted published procedure, we discovered that distillation under nitrogen produces cyclohexene in greater than 95% pure. This is suitable for use in cyclopropanation reactions.
Purification of Cyclohexene for Cyclopropanation Reactions
BEECH MTN. ROOM 120
Environmentally friendly reactions yielding cis-cyclopropanes are desired in the insecticide industry as these are most effective at reducing the population of insects while remaining benign to the environment. We are exploring the best parameters for the most effective cis-cyclopropanation reactions. An alkene and a diazo compound react together in the presence of a dirhodium catalyst to produce cyclopropanes. First however, the starting materials must be pure. Alfa Aesar supplies cyclohexene which is reported to be 99% pure, however, Gas column chromatography/Mass spectroscopy reveals that the sample is only 3% cyclohexene. Using an adopted published procedure, we discovered that distillation under nitrogen produces cyclohexene in greater than 95% pure. This is suitable for use in cyclopropanation reactions.