Midway Honors, Honors in Chemistry
Date of Award
Thesis Professor Department
Biochemistry and Molecular Biology
Karen Kornweibel, Antonio Rusinol
Vascular calcification is strongly correlated with the clinical manifestations of atherosclerosis, heart attacks and strokes. The calcification process resembles bone formation and involves the osteogenic trans-differentiation of smooth muscles cells within the arterial wall. Cannabinoid receptors are known to modulate bone formation and are present in atherosclerotic vessels, suggesting they may also play a role in modulating calcification. Therefore, we evaluated the effects of cannabinoids on the expression of osteogenic proteins by vascular smooth muscle cells undergoing calcification.
East Tennessee State University
Honors Thesis - Withheld
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Eccles, Bree A., "Effect of Cannabinoids on Osteogenic Differentiation of Cultured Vascular Smooth Muscle Cells" (2017). Undergraduate Honors Theses. Paper 392. https://dc.etsu.edu/honors/392
Copyright by the authors.
Available for download on Sunday, April 14, 2019