Functionalization of Silica Gel by Ultrasound-Assisted Surface Suzuki Coupling
Mesoporous silica gel was functionalized by various organic functional groups using thiol-ene coupling of surface thiol groups with 4-vinylphenylboronic acid followed by Suzuki coupling with aromatic halides. For better performance, the synthesis was conducted under sonication. The presence of surface functional groups was confirmed by thermoanalysis, FT-IR spectroscopy and characteristic reactions of these groups. Solid-phase conditions of the synthesis eliminate the risk of side reactions of boronic acids.
Kuvayskaya, Anastasia; and Vasiliev, Aleksey. 2019. Functionalization of Silica Gel by Ultrasound-Assisted Surface Suzuki Coupling. Tetrahedron Letters. Vol.60(37). https://doi.org/10.1016/j.tetlet.2019.07.028 ISSN: 0040-4039