Understanding Antimicrobial Resistance

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Bacteria are remarkably adaptable organisms with an innate ability to circumvent damage if exposed to a toxic environment. Antimicrobial-resistant bacteria are present worldwide, and many common infections are becoming more difficult to treat. Continued resistance is rapidly eliminating treatment options for patients, and the cost burden to treat a multidrug-resistant infection is climbing. Owing to the substantial costs associated with drug development, the introduction of novel antibiotics has lagged behind the increase in bacterial resistance. To address this crisis, pharmacists can take an active role in antimicrobial stewardship and foster understanding of how bacteria evade even the strongest available antimicrobial agents.