Title

Failure of Ceftolozane-Tazobactam Salvage Therapy in Complicated Pneumonia With Lung Abscess

Document Type

Article

Publication Date

7-1-2018

Description

Treatment of Pseudomonas aeruginosa remains challenging, despite the availability ceftolozane-tazobactam. We report a treatment failure with ceftolozane-tazobactam salvage therapy for pneumonia complicated by lung abscess. Drug resistance, dose selection, and source control are possible contributing factors. Ceftolozane-tazobactam susceptibility testing should precede therapy and consideration should be given to dosing selection.

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