Degree Name
MS (Master of Science)
Program
Chemistry
Date of Award
8-2014
Committee Chair or Co-Chairs
Dr. Jeffrey Wardeska
Committee Members
Dr. Scott Kirkby, Dr. Cassandra T. Eagle
Abstract
Vanadium haloperoxidases (VHPOs) are enzymes that catalyse the oxidation of halide ions to hypohalous acids by hydrogen peroxide. There are many unanswered questions on the mechanism by which the oxidation reaction occurs. In this work, is reported the synthesis of [VO(O2)H2EDTA], studies of the effect of acid concentration on the decomposition of [VO(O2)HEDTA]-2, and mechanistic studies of the rate law. The decomposition reaction was found to be first order with respect to acid concentration and also [VO(O2)HEDTA]-2 concentration. The reaction of [VOHEDTA]-1 and hydrogen peroxide progressed via a free radical path way. In addition, the vanadium(V) complex [VO(O2)H2EDTA] was synthesized and characterised by FT-IR, UV-VIS and GC-MS. The catalytic properties of [VO(O2)H2EDTA] were investigated for an oxibromination reaction. It was found that the catalysed, and the control reaction showed no major differences except for the fact that the reaction with the catalyst gave a dibrominated product without a carbonyl group.
Document Type
Thesis - unrestricted
Recommended Citation
Fon, Tinga C. O. Mr., "Synthesis and Characterization of [VO(O2)H2EDTA] and Investigation of the Reaction Between [VOHEDTA]-1 and Hydrogen Peroxide as a Model Catalyst for Haloperoxidases" (2014). Electronic Theses and Dissertations. Paper 2424. https://dc.etsu.edu/etd/2424
Copyright
Copyright by the authors.