Degree Name
MSEH (Master of Science in Environmental Health)
Program
Environmental Health
Date of Award
12-2011
Committee Chair or Co-Chairs
Brajesh Dubey
Committee Members
Kurt Maier, Philip Scheuerman, Thabet Tolaymat
Abstract
Silver nanoparticles (AgNPs) synthesized using numerous types of coating materials may exhibit different toxicity effects. The study evaluated coating material dependent toxicity by selecting 3 types of AgNP synthesis methods with different coating materials (citrate, polyvinyl pyrrolidone, and branched polyethyleneimine, coated AgNPs as citrate-AgNPs, PVP-AgNPs, and BPEI-AgNPs respectively). Two acute aquatic toxicity tests were performed; 48hr D. magna and MetPLATE E. coli toxicity tests. Significantly different toxicity effects were observed in D. magna test exhibiting lethal median concentrations (LC50) for citrate-AgNPs, PVP-AgNPs, and BPEI AgNPs respectively as, 2.7, 11.2, and 0.57μg/L. Median inhibitory concentrations (EC50) for MetPLATE tests were 1.27, 1.73, and 0.31mg/L respectively with significant different toxicity effects. Silver ion fractions were detected in the range of 2.4-19.2% in tested NP suspensions. Study suggests the toxicity effects are due to the cumulative action of ionic and nanoparticle fractions in the suspensions.
Document Type
Thesis - unrestricted
Recommended Citation
Silva, Thilini Upekshika, "An Evaluation of Coating Material Dependent Toxicity of Silver Nanoparticles" (2011). Electronic Theses and Dissertations. Paper 1229. https://dc.etsu.edu/etd/1229
Copyright
Copyright by the authors.