Microbiome Alterations in a Rat Model of Stress and Alcohol Exposure

Faculty Mentor

Dr. Michelle Chandley

Mentor Home Department

Biomedical Sciences

Short Abstract

The gut microbiome has been shown to modulate neurochemical pathways through the gut-brain axis. In this study, the microbiome expression patterns, along with their metabolites, were quantified using feces from an animal model of restraint stress and alcohol exposure. Alterations in bacterial expression patterns were identified using 16S ribosomal sequencing. These data are among the first to demonstrate that vapor exposed rats exhibit changes gut microbiota profiles.

Category

Science and Technology

Start Date

24-4-2023 1:45 PM

End Date

24-4-2023 2:00 PM

Location

D.P. Culp Center Room 271J

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Apr 24th, 1:45 PM Apr 24th, 2:00 PM

Microbiome Alterations in a Rat Model of Stress and Alcohol Exposure

D.P. Culp Center Room 271J

The gut microbiome has been shown to modulate neurochemical pathways through the gut-brain axis. In this study, the microbiome expression patterns, along with their metabolites, were quantified using feces from an animal model of restraint stress and alcohol exposure. Alterations in bacterial expression patterns were identified using 16S ribosomal sequencing. These data are among the first to demonstrate that vapor exposed rats exhibit changes gut microbiota profiles.