Understanding Why, When, and How Cancer Influences Substance Use Behavior Among Appalachian Patients: A Descriptive Analysis of Linking Survey Items

Additional Authors

Bill Brooks

Abstract

Cancer and substance use disorder disproportionately impact Appalachian communities, yet little research examines how a cancer diagnosis itself may influence substance use behavior. This study aimed to understand why, when, and how cancer impacts substance use among Appalachian patients. The guiding research question was: Does a cancer diagnosis function as a trigger for substance use initiation or escalation? We hypothesized that cancer diagnosis would be associated with increased substance use due to psychological distress, pain management needs, and financial strain. This study addresses an important gap by going beyond documenting co-occurrence as it examines how and why cancer may influence substance use. Data was collected between June - August 2024 using an online cross-sectional survey. Participants were required to be 18 years or older, reside in Appalachia, and have a prior cancer diagnosis. Descriptive analyses of demographic variables and survey items assessing opioid prescribing, pre-diagnosis substance use, post-diagnosis changes in use, coping motivations, pain management substitution, treatment access barriers, and financial burden were conducted. A total of 31 people participated; the median age was 65, and 75% were female. More than half of the participants (59%) reported substance use before diagnosis, and 41% reported increased use following diagnosis. Substance use was frequently linked to psychological coping (71%). Almost half (47%) reported using substances for cancer-related pain management. Only 29% of participants believed their substance use was directly related to their cancer diagnosis. Additionally, 35% reported substances were easier to obtain than traditional treatment, while only 6% indicated cost of treatment influenced substance use. Overall, findings suggest substance use among cancer survivors in this Appalachian-region convenience sample was more strongly associated with coping and symptom management than with treatment access or financial barriers. The identification of behavioral pathways informs intervention targets.

Start Time

15-4-2026 9:00 AM

End Time

15-4-2026 10:00 AM

Room Number

304

Presentation Type

Oral Presentation

Presentation Subtype

Grad/Comp Orals

Presentation Category

Health

Student Type

Graduate

Faculty Mentor

Mildred Maisonet

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Understanding Why, When, and How Cancer Influences Substance Use Behavior Among Appalachian Patients: A Descriptive Analysis of Linking Survey Items

304

Cancer and substance use disorder disproportionately impact Appalachian communities, yet little research examines how a cancer diagnosis itself may influence substance use behavior. This study aimed to understand why, when, and how cancer impacts substance use among Appalachian patients. The guiding research question was: Does a cancer diagnosis function as a trigger for substance use initiation or escalation? We hypothesized that cancer diagnosis would be associated with increased substance use due to psychological distress, pain management needs, and financial strain. This study addresses an important gap by going beyond documenting co-occurrence as it examines how and why cancer may influence substance use. Data was collected between June - August 2024 using an online cross-sectional survey. Participants were required to be 18 years or older, reside in Appalachia, and have a prior cancer diagnosis. Descriptive analyses of demographic variables and survey items assessing opioid prescribing, pre-diagnosis substance use, post-diagnosis changes in use, coping motivations, pain management substitution, treatment access barriers, and financial burden were conducted. A total of 31 people participated; the median age was 65, and 75% were female. More than half of the participants (59%) reported substance use before diagnosis, and 41% reported increased use following diagnosis. Substance use was frequently linked to psychological coping (71%). Almost half (47%) reported using substances for cancer-related pain management. Only 29% of participants believed their substance use was directly related to their cancer diagnosis. Additionally, 35% reported substances were easier to obtain than traditional treatment, while only 6% indicated cost of treatment influenced substance use. Overall, findings suggest substance use among cancer survivors in this Appalachian-region convenience sample was more strongly associated with coping and symptom management than with treatment access or financial barriers. The identification of behavioral pathways informs intervention targets.