A Case Report of Catastrophic Antiphospholipid Syndrome with Libman-Sacks Presenting as Interstitial Pneumonia

Authors' Affiliations

Chassidy Sumler Martin, Lincoln Memorial University - DeBusk College of Osteopathic Medicine, Harrogate, TN Rocco Cannistraro, Fort Sanders Regional Medical Center, Knoxville, TN

Location

Culp Center Rm. 303

Start Date

4-25-2023 4:00 PM

End Date

4-25-2023 4:20 PM

Faculty Sponsor’s Department

Other - please list

Neurologist

Name of Project's Faculty Sponsor

Rocco Cannistraro

Classification of First Author

Medical Student

Competition Type

Competitive

Type

Oral Presentation

Project's Category

Immune System, Autoimmunity

Abstract or Artist's Statement

A Case Report of Catastrophic Antiphospholipid Syndrome with Libman-Sacks Presenting as Interstitial Pneumonia

Chassidy Sumler Martin, MS, Rocco Cannistraro, MD

Antiphospholipid syndrome (APS) is an autoimmune condition characterized by vascular thromboses and a positive antiphospholipid antibody. Catastrophic antiphospholipid syndrome (CAPS) is a rare disease that often results in death. CAPS is the most severe form of APS, which can develop in a short period of time and occurs in less than 1% of people with APS. CAPS involves multiple organs simultaneously with diffuse microvascular and macrovascular involvement. Here, we present a case of catastrophic antiphospholipid syndrome presenting as interstitial pneumonia that rapidly progressed to acute renal failure, acute ischemic cerebral infarcts, cardiac valvular vegetations, and heart failure. This case report aims to bring awareness of prompt medical suspicion and treatment of CAPS in hopes of improving disease outcomes.

This document is currently not available here.

Share

COinS
 
Apr 25th, 4:00 PM Apr 25th, 4:20 PM

A Case Report of Catastrophic Antiphospholipid Syndrome with Libman-Sacks Presenting as Interstitial Pneumonia

Culp Center Rm. 303

A Case Report of Catastrophic Antiphospholipid Syndrome with Libman-Sacks Presenting as Interstitial Pneumonia

Chassidy Sumler Martin, MS, Rocco Cannistraro, MD

Antiphospholipid syndrome (APS) is an autoimmune condition characterized by vascular thromboses and a positive antiphospholipid antibody. Catastrophic antiphospholipid syndrome (CAPS) is a rare disease that often results in death. CAPS is the most severe form of APS, which can develop in a short period of time and occurs in less than 1% of people with APS. CAPS involves multiple organs simultaneously with diffuse microvascular and macrovascular involvement. Here, we present a case of catastrophic antiphospholipid syndrome presenting as interstitial pneumonia that rapidly progressed to acute renal failure, acute ischemic cerebral infarcts, cardiac valvular vegetations, and heart failure. This case report aims to bring awareness of prompt medical suspicion and treatment of CAPS in hopes of improving disease outcomes.